黄海 教授
E-mail: huanghai@cczu.edu.cn
课题组网页：https://www.x-mol.com/groups/huanghaicczu
教育经历
2016.02-2017.01 美国内华达大学拉斯维加斯分校，博士联合培养，导师: Prof. Jun Yong Kang
2011.09-2016.12 南京工业大学，博士学位，导师: 朱红军 教授
2007.09-2011.07 南京工业大学，学士学位
工作经历
2020.01-至今 welcome欢迎光临威尼斯公司，教授
2019.05-2019.12 welcome欢迎光临威尼斯公司，一类雇员（香港科技大学博士后身份）
2018.07-2019.12 香港科技大学，博士后，合作导师: Prof. Jianwei Sun
2017.02-2018.04 美国内华达大学拉斯维加斯分校，博士后，合作导师: Prof. Jun Yong Kang.
承担项目
国家自然科学基金青年基金（22201023），30万，2023-2025
企业技术开发项目，60万，2022-2024
江苏省中以产业技术研究院开放课题（JSIITRI202205），3万，2022
江苏省双创人才（JSSCRC2021536），50万，2021-2024.
江苏省自然科学青年基金（BK20210849），20万，2021-2024.
国家自然基金重大研究计划-培育项目（91956114），37.5万，2020-2022.
江苏省高等学校自然科学研究面上项目（20KJB150012），5万，2020-2022.
常州市应用基础研究计划（CJ20200082），5万，2020-2022.
国家博士后基金-B类资助（2018M642226），5万，2018-2019.
江苏省博士后基金-A类资助（2018K027A），8万，2018-2019.
获奖情况
2020年度 ACS 个人贡献奖
2020年度 常州市十大青年科技新锐
2021年度 常州市第十六次自然科学优秀论文一等奖
科研方向
有机合成方法学：炔烃导向性官能团化，不对称催化，光催化等
论文发表
2022年
34. Hongling Xie, Zhenkun Yang, Luning Tang, Zhengyu Han,* Jianwei Sun,* and Hai Huang.* Construction of Nine-memberedN,N,O-Heterocycles via Pdcatalyzed [6+3] Dipolar Cycloaddition.Chem. Commun.,2022,58, 10560-10563.
30. Danfeng Wang, Hai Huang*, Xiaolin Zhu*. Development of Anthrazoline Photocatalyst for Promoting Amination and Amidation Reactions. Chem. Commun. 2022, 58, 3529-3532.
29. Tianyu Zhang, Han Zhuang, Luning Tang, Zhengyu Han, Wengang Guo, Hai Huang,* and Jianwei Sun*. Catalytic Enantioselective Synthesis of 2,3-Dihydrobenzo[b]oxepines via Asymmetric Oxetane Opening by Internal Carbon Nucleophiles. Org. Lett.2022, 24, 207-212.
2021年
27. Tianyu Zhang, Zhenkun Yang, Dapeng Zhou, Fuliang Meng, Zhengyu Han*, Hai Huang*.Non-metal Lewis acid-catalyzed cross-Claisen condensation for β-keto esters. Org. Biomol. Chem. 2021, 19, 9163-9166.
26. Shuxuan Liu, Hui Qian, Tianyu Zhang, Hongling Xie, Zhengyu Han, Wengang Guo, Hai Huang,* and Jianwei Sun*.Mild Intermolecular Synthesis of a Cyclopropane-Containing Tricyclic Skeleton: Unusual Reactivity of Isobenzopyryliums. Angew. Chem. Int. Ed.2021, 60, 21272-21276.
25. Wengang Guo, Min Wang, Zhengyu Han, Hai Huang* and Jianwei Sun*. Organocatalytic asymmetric synthesis of a-amino esters from sulfoxonium ylides. Chem. Sci., 2021, 12, 11191-11196.
24. Song Sun, Zhaobin Wang, Shijia Li, Cong Zhou, Lijuan Song, Hai Huang,* and Jianwei Sun*. An Organocatalytic Kinetic Resolution of Aziridines by Thiol Nucleophiles. Org. Lett.2021, 23, 554-558.
23. Hai Huang, Tianyu Zhang, and Jianwei Sun*. Mild C–C Bond Formation via Lewis Acid Catalyzed Oxetane Ring Opening with Soft Carbon Nucleophiles. Angew. Chem. Int. Ed. 2021, 60, 2668-2673.Highlighted by CBG.
22. Shuxuan Liu, Yu Zang, Hai Huang*, and Jianwei Sun*. In(OTf)3-Catalyzed Synthesis of 2,3-Dihydro-1H-benzo[e]indoles and 2,3-Dihydrobenzofurans via [3 + 2] Annulation. Org. Lett. 2020, 22, 8219-8223.
21. Guannan Wang#, Hai Huang#, Wengang Guo, Chenxiao Qian, Jianwei Sun,*Unusual Skeletal Reorganization of Oxetanes for the Synthesis of 1,2-Dihydroquinolines.Angew. Chem. Int. Ed. 2020, 59,11245-11249.(# Co-first author)Highlighted by Synfacts.
2019年
20. Hai Huang, Wen Yang, Zuliang Chen, Zengwei Lai, Jianwei Sun,* A mild catalytic synthesis of 2-oxazolines via oxetane ring-opening: rapid access to a diverse family of natural products. Chem. Sci., 2019, 10, 9586-9590.
入职welcome欢迎光临威尼斯公司前
19. Hai Huang, Johanna Denne, Chou-Hsun Yang, Haobin Wang, Jun Yong Kang.* Direct Aryloxylation/Alkyloxylation of Dialkyl Phosphonates for the Synthesis of Mixed Phosphonates [J]. Angew. Chem. Int. Ed. 2018, 57, 6624-6628. (Highlighted by UNLV news; Highlighted by Synpacts)
18. Hai Huang, Jun Yong Kang.* New Strategies for Activation of Phosphonates/Phosphates toForge Functional Phosphorus Compounds [J]. Synlett, 2019, 30, 635-641.
17. Hai Huang, Jeffrey Ash, Jun Yong Kang.* Tf2O Promoted Activating Strategy of Phosphate Analogues: Synthesis of Mixed Phosphates and Phosphinate [J]. Org. Lett.2018, 20, 4938-4941. (Highlighted by Organic Chemistry Portal).
16. Hai Huang, Jeffrey Ash, Jun Yong Kang.*Base-Controlled Fe(Pc)-Catalyzed Aerobic Oxidation of Thiols for the Synthesis of S-S and S-P(O) Bond [J]. Org. Biomol. Chem.2018, 16, 4236-4242.
15. Hai Huang, Hongjun Zhu, Jun Yong Kang.* Regio- and Stereoselective Hydrophosphorylation of Ynamides for the Synthesis of β-Aminovinylphosphine Oxides [J]. Org. Lett.2018, 20, 2778-2781.
14. Manasa Shetty,# Hai Huang,# Jun Yong Kang.* Regioselective Synthesis of α- and γ-Amino Quinolinyl Phosphonamides using N-Heterocyclic Phosphines (NHPs) [J]. Org. Lett.2018, 20, 700-703. (# Co-first author)
13. Hai Huang, Jun Yong Kang.* Organocatalytic Phosphonylation of in Situ Formed o Quinone Methides [J]. Org. Lett. 2017, 19, 5988-5991.
12. Hai Huang, Jun Yong Kang.* Oxidation-Reduction Condensation of Diazaphosphites for Carbon-Heteroatom Bond Formation Based on Mitsunobu Mechanism [J]. Org. Lett. 2017, 19, 544-547.
11. Luning Tang,# Hai Huang,# Yang Xi, Guangke He, Hongjun Zhu.* Pd/Cu-Catalyzed Tandem Head-to-tail Dimerization/Cycloisomerization of Terminal Ynamides for the Synthesis of 5-Vinyloxazolones [J]. Org. Biomol. Chem.2017, 15, 2923-2930 (# Co-first author)
10. Hai Huang, Jun Yong Kang.* Mitsunobu Reaction Using Basic Amines as Pronucleophiles [J]. J. Org. Chem. 2017, 82, 6604-6614. (Most Read Articles in JOC, 2017; Highlighted in Synfacts, 2017, 13, 807)
9. Hai Huang, Jake Palmas, Jun Yong Kang.* A Reagent-Controlled Phospha Michael Addition Reaction of Nitroalkenes with Bifunctional N-Heterocyclic Phosphine (NHP) Thioureas [J]. J. Org. Chem. 2016, 81, 11932-11939.
8. Hai Huang, Luning Tang, Xiaobo Han, Guangke He, Yang Xi, Hongjun Zhu.* Regioselective Iodoamination of Terminal Ynamides for the Synthesis of α-amino-β,β-diiodo-enamides [J]. Chem. Commun., 2016, 52, 4321-4324.
7. Hai Huang, Luning Tang, Qi Liu, Yang Xi, Guangke He,* Hongjun Zhu.* Formation of α-Chalcogenyl Acrylamides through Unprecedented Chalcogen Mediated Metal-Free Oxyfunctionalization of Ynamides with DMSO as Oxidant. Chem. Commun., 2016, 52, 5605-5608.
6. Hai Huang, Jun Yong Kang.* Amine-Catalyzed Phospha-Michael Reaction of α, β-Unsaturated Aldehydes and Ketones with Multifunctional N-Heterocyclic Phosphine-Thioureas as Phosphonylation Reagent. Org. Lett., 2016, 18, 4372-4375.
5. Hai Huang, Junzhen Fan, Guangke He,* Zhimin Yang, Xiaodong Jin, Qi Liu, Hongjun Zhu.* Generation of Oxazolidine-2,4-diones Bearing Thio-Quaternary Carbons by Oxothiolation / Cyclization of Ynamides. Chem. Eur. J., 2016, 22, 2532-2538.
4. Hai Huang, Luning Tang, Yang Xi, Guangke He, Hongjun Zhu.* Metal-free Hydration of Ynamides: Convenient Approach to Amides. Tetrahedron Lett.,2016, 57, 1873-1876.
3. Hai Huang, Guangke He, Guohao Zhu, Xiaolin Zhu, Shineng Qiu, Hongjun Zhu.* Palladium-Catalyzed Intramolecular Cyclization of Ynamides: Synthesis of 4-Halo-oxazolones. J. Org. Chem., 2015, 80, 3480-3487.
2. Hai Huang, Xiaolin Zhu, Guangke He, Qi Liu, Junzhen Fan, Hongjun Zhu.* Controlled Synthesis of 1,3,5-Oxadiazin-2-ones and Oxazolones through Regioselective Iodocyclization of Ynamides. Org. Lett., 2015, 17, 2510-2513.
1. Hai Huang, Guangke He, Xiaolin Zhu, Xiaodong Jin, Shineng Qiu, Hongjun Zhu.* Iodine-Mediated Oxidation of Ynamides: A Facile Access to N-Monosubstituted α-Ketoamides and α-Ketoimides. Eur. J. Org. Chem., 2014, 7174-7183.
